FORMATION OF NEW AURANTINE FRACTIONS AND STUDY OF THEIR CHEMICAL AND BIOLOGICAL PROPERTIES,
Abstract
The conditions of formation of new aurantine fractions, their chemical composition, and their biological properties were investigated. It is shown that all fractions, as well as the original aurantine, prolong to a greater or lesser extent the life of mice with leucosis. The antileucosis effect is increased with increase in the general toxic action of any of the preparations. The various fractions are not equally toxic. In par ticular, the fractions which contain leucine in their structure (Au5 and Au7) have a lower toxic activity. This makes it possible to vary the dosages of these preparations over a wide range while maintaining an antileucosis effect which is the same (relative to the other fractions). (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 02, 1963
- Accession Number
- AD0410704
Entities
People
- M.v. Nefelova
- V.n. Shaposhnikov
Organizations
- Joint Publications Research Service