RATE OF RED CELL FORM < IN RATS AT 24 DEGREES C AND AT 5 DEGREES C,
Abstract
Radioautography of peripheral blood subsequent to Fe59 administration was employed to determine the rate of erythrocyte formation in male Sprague Dawley rats maintained at 24 C and after exposure to 5 C for 4, 5, and 6 weeks. The rate at which newly-formed labeled cells appeared in the blood was approximately 3 per cent per day of the total circulating erythrocyte population for both con trol and experimental animals. This rate was the same for animals of two body weight ranges, 150 to 200 grams and 300 to 400 grams. Assuming that the rate of new red cell formation is equal to the rate of red cell destruction, the circulating life span of the rat erythrocytes is estimated to be approximately 33 days. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1962
- Accession Number
- AD0410780
Entities
People
- N.b. Everett
- R.w. Caffrey