THE EFFECT OF UDMH INJECTION ON COMPLEX AVOIDANCE BEHAVIOR IN THE JAVA MONKEY

Abstract

Four java monkeys were injected with 30 mg/kg of 1,1- dimethylhydrazine (UDMH) and their performance on a four-component operant schedule was compared with their performance under control conditions. In every instance where a performance decrement occurred (9 out of a possible 32), there was also associated clinical illness in the form of hyperactivity, nausea, vomiting, or lethargy. One subject showed no impairment following the two UDMH injections, while another subject exhibited an impairment on all four tasks during the second replication; this suggests the range of individual reactivity to UDMH exposure, and that repeated severe exposure may cause serious decrement of performance. From these data, one may expect clinical signs of illness after 2 to 3 hours, a performance decrement or change after 3 to 3-1/2 hours, and recovery to pre-exposure level of functioning between six and nine hours.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1963
Accession Number
AD0410933

Entities

People

  • Frederick H. Rohles
  • Henry W. Brunson
  • Herbert H. Reynolds
  • James R. Prime
  • Vernon L. Carter

Tags

Communities of Interest

  • Biomedical
  • Space

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Animals
  • Biomedical Research
  • Energetic Materials
  • Experimental Data
  • Fuels
  • Government Procurement
  • Governments
  • Laboratory Animals
  • Materials
  • Materials Laboratories
  • Monitoring
  • New Mexico
  • Performance Tests
  • Seizures
  • Sequences

Fields of Study

  • Psychology

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Toxicology/Environmental Toxicology
  • Underwater engineering and Marine Technology.