INFLUENCE OF LOW AMBIENT TEMPERATURE ON RESIST ANCE OF MICE TO EXPERIMENTAL COXSACKIE VIRUS INFECTION,

Abstract

Adult albino mice were challenged intraperi toneally with Type B-1 Coxsackie virus under conditions of acclimatization and nonacclimati zation to 1 C. The results show that exposure of unacclimatized mice to 2 C results in lowered host resistance but that specific immunization is effective in protection under these conditions. Mice acclimatized to 2 C for 40 days have in creased resistance to challenge that is independ ent of specific immunization procedures. The mechanisms involved in protection under these circumstances remain to be explored. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1963
Accession Number
AD0412563

Entities

People

  • F. Miya
  • J. Spencer
  • L. J. Phelps
  • S. Marcus

Organizations

  • University of Utah

Tags

DTIC Thesaurus Topics

  • Acclimatization
  • Bacterial Infections And Mycoses
  • Diseases And Disorders
  • Immune System Phenomena
  • Immunization
  • Immunomodulation
  • Infection
  • Resistance
  • Resistance (Biology)
  • Wound Infections

Readers

  • Marine Mammal Biology
  • Snow Cover Descriptors for Reptiles and Their Illustrations.
  • Virology (or Medical Virology).