THE EFFECT OF ANTIMETABOLITE THERAPY ON CHROMOSOME MORPHOLOGY OF BONE MARROW AND PERIPHERAL BLOOD LEUKOCYTES IN ACUTE LYMPHOCYTIC AND MYELOGENOUS LEUKEMIA.

Abstract

Chromosomal analyses were performed on specimens of peripheral blood leukocytes and bone marrow cells of two patients with acute lymphocytic leukemia. The modal counts and morphology before and after treatment with vincristine (2 mg/square meters/week) were indistinguishable from normal. Further studies are now in progress. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1963
Accession Number
AD0413489

Entities

People

  • Robert G. Scherz

Organizations

  • Walter Reed Army Institute of Research

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Antimetabolites
  • Biological Sciences
  • Blood
  • Bone Marrow
  • Bone Marrow Cells
  • Bones
  • Cells
  • Cells (Biology)
  • Chromosomes
  • Leukemia
  • Leukocytes

Fields of Study

  • Medicine

Readers

  • Molecular and genetic basis of cancer.
  • Oncology (Cancer Research).
  • Toxicology/Environmental Toxicology