EFFECT OF HYPOXIA ON THE RATE OF OXYGEN CONSUMPTION OF NEWBORN, YOUNG, AND ADULT MICE AT VARIOUS ENVIRONMENTAL TEMPERATURES,
Abstract
Critical Po2 that is, Po2 below the point at which oxygen consumption is reduced - was measured in newborn, 5-day-old, and adult mice. At thermoneutral environmental temperatures, the critical Po2 of newborn was 85 mm. Hg; that of 5-day-old mice was 100 mm. Hg; and that of adults was 70 mm. Hg. When ambient temperature was lower than the thermoneutral point, the critical Po2 was higher. The extra oxygen consumption used to combat the lowering of body temperature appeared to make the animal more vulnerable to hypoxia. Although the newborn mouse cannot resist hypothermia effectively, there was a slight increase in its oxygen consumption in response to mild hypothermia. Maximal oxygen consumption occurred at lower temperatures in the 5-day-old mouse than in the 1-day-old. Evidently, there is a rapid maturation of temperature-controlling mechanisms during growth. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1963
- Accession Number
- AD0414926
Entities
People
- S. Cassin
Organizations
- University of Florida