EFFECTS OF HIGH CONCENTRATIONS OF CARBON DIOXIDE AND DIET ON URINARY EXCRETION OF STEROIDS AND CATECHOLAMINES

Abstract

Air Force pilots were exposed to inspired tracheal PCO2 of 21 mm. Hg (BTPS) at 700 mm. Hg and 200 mm. Hg cabin pressure. Each exposure was of 4 days' duration and was preceded in each case by a control period of low CO2 also of 4 days' duration at the equivalent cabin pressures. During the entire experiment, including pre- and post experiment control periods, the subjects were given a special liquid diet. The effects of CO2 and diet on the endocrine functions were studied by determining the urinary excretion of epinephrine, norepinephrine, 17-OHCS, and corticoster one-like hormones. It was found that the CO2, both at ground and at simulated altitude, in creased the excretion of epinephrine, norepinephrine, and corticosterone-like hormones. CO2 at simulated altitude had a stronger effect than at ground level. The special liquid diet caused increased excretion of epinephrine, while the excretion of the other three hormone groups decreased.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1963
Accession Number
AD0419149

Entities

People

  • B.e. Welch
  • Frode Ulvedal
  • R.g. Cutler

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aerospace Medicine
  • Aviation Medicine
  • Blood
  • Body Weight
  • Carbohydrates
  • Carbon Dioxide
  • Catecholamines
  • Dehydrated Foods
  • Endocrine Glands
  • Epinephrine
  • Food
  • Ground Level
  • Medical Personnel
  • Metabolism
  • Norepinephrine
  • Rodents
  • Sea Level

Fields of Study

  • Chemistry

Readers

  • Cardiovascular Physiology
  • Exercise and Sports Science.