FIBRONOLYTIC ACTIVITY OF PASTEURELLA PESTIS

Abstract

The purpose of this study was to survey a number of strains, both virulent and avirulent, for fibrinolytic activity and to determine its relationship to virulence. A modification of the purified fibrin clot technique of Tillet and Garner was used in conjunction with the fibrin film technique of Astrup and Mullertz. Various strains of virulent and avirulent organisms were grown at 26 degrees or 37 degrees under both aerobic and anaerobic conditions. Results showed that all nine virulent strains tested were capable of causing fibrin lysis both at 26 degrees and 37 degrees C.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1963
Accession Number
AD0422349

Entities

People

  • E. D. Beesley
  • W. A. Janssen

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Bacteria
  • Biological Laboratories
  • Biomedical Research
  • Blood Coagulation Factors
  • Calcium Compounds
  • Cells
  • Fibrin
  • Fibrinogen
  • Films
  • Laboratory Animals
  • Materials
  • Microorganisms
  • Rodents
  • Test Methods
  • United States
  • Virulence

Fields of Study

  • Biology

Readers

  • Immunology
  • Marine Mammal Biology