METABOLISM OF C1 COMPOUNDS BY MICROORGANISMS,
Abstract
Growth of Pseudomonas methanicaon methane or methanol as sole carbon source has been studied by following the course of incorporation of (C14) labelled growth substrate into cell constituents using chromatographic and radioautographic techniques. It has been found that radioactivity from either (C14) methane or (C14) methanol appears most rapidly in phosphorylated compounds. This is in contrast with the incorporation of (C14) methanol or (C14) formate into Pseudomonas AM1 growing respectively on methanol or formate, where fixation occurs predominantly into serine. The new results with Pseudomonas methanica suggest the possibility of a different pathway. A thiamine pyrophosphate-dependent hydroxymethylation of pentose phosphate has been suggested as one such possibility. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1943
- Accession Number
- AD0422920
Entities
People
- Hans Krebs
- J. R. Quayle
Organizations
- University of Oxford