EFFECTS ON MAN OF PROLONGED EXPOSURE TO OXYGEN AT A TOTAL PRESSURE OF 190 MM. HG

Abstract

Four 17-day experiments were conducted on healthy pilots in the two- man space cabin simulator. Total pressure averaged 192 mm. Hg; partial pressure of oxygen, 174 mm. Hg. This atmosphere was reasonably well tolerated by all test subjects. The symptoms consisted of irritation of the upper respiratory tract, aural atelectasis, and eye irritation. Postexperimentally, 2 of the 8 subjects demonstrated reduced arterial oxygen saturation immediately. Pictures, however, gave no x-ray evidence of pulmonary atelectasis. The incidence of baropathies following decompression from 750 mm. Hg to 190 mm. Hg exceeded 50% (5 of 8 subjects), even following 2 to 3 hours of preoxygenation. The utilization of an atmosphere consisting of oxygen, carbon dioxide, and water vapor at total pressure of 190 mm. Hg appears to be physiologically feasible, at least for 17 days. Care must be taken to overcome the problem of bends during the initial decompression and to insure that engineering gains are sufficiently great to offset the symptoms noted in these studies. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1963
Accession Number
AD0423948

Entities

People

  • B. E. Welch
  • Ralph G. Cutler
  • Thomas E. Morgan Jr.

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Barometric Pressure
  • Carbon Dioxide
  • Cardiac Arrhythmias
  • Cardiovascular Physiological Phenomena
  • Decompression
  • Engineering
  • Environment
  • Government Procurement
  • Ground Level
  • Health Services
  • Lung Diseases
  • Medical Personnel
  • Partial Pressure
  • Sea Level
  • Vapor Pressure
  • Water Vapor
  • X Rays

Readers

  • Mathematics or Statistics
  • Toxicology/Environmental Toxicology
  • Underwater engineering and Marine Technology.

Technology Areas

  • Space