FACTORS AFFECTING PLAQUE FORMATION BY THE INFECTIOUS RIBONUCLEIC ACID OF THE EQUINE ENCEPHALITIS VIRUSES

Abstract

Factors that influence plaque formation by the infectious RNA of the equine encephalitis viruses were studied. Optimal conditions were found that provided a very sensitive and reliable assay system for the infectious RNA of this group of viruses. There was a linear relationship between plaque counts in monolayers and the dilution of the RNA applied. The frequency distribution of plaques formed by infectious RNA is of the Poisson type, suggesting that one RNA molecule gives one plaque.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1963
Accession Number
AD0424663

Entities

People

  • Jane B. Idoine
  • Julio I. Colon

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Acids
  • Animal Diseases
  • Anti-Bacterial Agents
  • Arbovirus Infections
  • Biological Sciences
  • Cell Count
  • Chemistry
  • Dilution
  • Diseases And Disorders
  • Encephalitis
  • Equine Encephalitis
  • Fibroblasts
  • Indicator Dyes
  • Molecules
  • Monomolecular Films
  • Ribonucleic Acids
  • Viruses

Fields of Study

  • Biology

Readers

  • Molecular Genetics
  • Virology (or Medical Virology).