MECHANISM OF ENZYME ACTION.
Abstract
The carboxylic groups and SH groups play impor tant roles in hydrolytic plant-enzymes like papain and ficin. A cooperative effect of imidazole groups and mercapto or carboxylic groups are important in the action of several glycolytic enzymes. In addition, electrostatic attraction to the carboxylate anion in choline esterase may help the catalytic hydrolysis of the imidazole groups on the enzyme from a 'neighboring group' position. The synthetics of homopolymers, copolymers and appropriate substrates and the kinetic studies performed so far were done in order to attain further insight into the mechanism of action of the afore mentioned hydrolytic enzymes. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 28, 1963
- Accession Number
- AD0426885
Entities
People
- C. G. Overberger
- Joseph J Lee
- R. Sitaramaiah
- Samuel Yaroslavsky
- Thomas St. Pierre
Organizations
- New York University Tandon School of Engineering