ABILITY OF A FISH CELL LINE TO SUPPORT GROWTH OF MAMMALIAN VIRUSES,

Abstract

A fish cell line derived from rainbow trout gonads (RTG) has been shown to support the proliferation of two arboviruses (Venezualan equine encephalitis (VEE) virus and Eastern equine encephalitis (EEE) virus) at 22 C. EEE virus was more cytopathogenic for RTG cultures than VEE virus, thus making it feasible to distinguish between the two. A persistent infection was obtained with VEE virus for as long as cultures were carried, but not with EEE virus. Both viruses multiplied in chick fibroblast (CF) cells at 22 C to slightly higher titers than in the fish cell line, and both viruses caused a cytopathogenic effect in CF cells. L cells failed to support the growth of either virus at 22 C. (Author)

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1963
Accession Number
AD0428177

Entities

People

  • Julius E. Officer Jr.

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Cell Line
  • Cells
  • Encephalitis
  • Equine Encephalitis
  • Fish
  • Infection
  • Virus Diseases
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Aquatic Ecology
  • Virology (or Medical Virology).