ON THE GROWTH MECHANISM OF PSITTACOSIS-TRACHOMA VIRUSES IN TISSUE CULTURES

Abstract

Trachoma virus has been successfully adapted to HeLa cell. The virus passes through eclipse phase during the multiplication and seems to arise from the matrix material, therefore there is no immediate morphological continuity between the infected particles and the new generation of the virus. There is no evidence that trachoma viruses multiply by vinary fission which had been supposed so far. It was found that the preparations of meningopneumonitis virus (MPV) purified by a combination of differential centrifugation, treatments by nucleases and trypsin, and sucrose density gradient centrifugation consisted mostly of elementary bodies of the virus. Chemical analysis of the elementary body showed that it contained approximately equal amount of ribo-and deoxyribonucleic acid.

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Document Details

Document Type
Technical Report
Publication Date
Feb 04, 1963
Accession Number
AD0432204

Entities

People

  • Noboru Higashi

Organizations

  • Kyoto University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acids
  • Albumins
  • Anti-Bacterial Agents
  • Cells
  • Chemical Analysis
  • Chlamydia
  • Culture Techniques
  • Deoxyribonucleic Acids
  • Electron Microscopes
  • Electron Microscopy
  • Fission
  • Government Procurement
  • Infection
  • Materials
  • Microscopy
  • Nucleic Acids
  • Perchloric Acid

Readers

  • Calculus or Mathematical Analysis
  • Virology (or Medical Virology).