MYOCARDITIS IN NORMAL RHESUS (MACACA MULATTA) MONKEYS
Abstract
A clinical-pathological study was undertaken to ascertain the etiology of myocarditis seen in 18 of 20 normal rhesus monkeys. The results of this study indicate that the myocarditis is not due to a virus that kills suckling mice, nor to bacteria. Moreover, viral inclusion bodies or parasites were not demonstrated morphologically in the myocardium. The myocarditis is most probably idiopathic. Inclusion bodies of salivary gland virus localized to the kidneys of 6 of the 20 monkeys have been described. The significance of slightly elevated SGOT and SGPT values and the presence and significance of multinucleated hepatic parenchymal cells are discussed. Additional hematological and clinical chemistry values are recorded, as are both gross and microscopic anatomical data.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1964
- Accession Number
- AD0432433
Entities
People
- Francis A. Beall
- Lazarus L. Kupferberg
- Peter J. Soto Jr.
- Robert M. Nakamura
Organizations
- United States Army Biological Warfare Laboratories