OXYGEN AND THE EYE
Abstract
The current interest in biomedical research, calling for human beings to be subjected to prolonged exposure to high oxygen environments, requires careful consideration of the possible hazards involved. A review of the literature clearly indicates that oxygen is capable of producing severe systemic toxicity. In the 1950's it was found that prolonged exposure to oxygen was responsible for retrolental fibroplasia in premature infants. Consideration of the physiology of increased oxygen tensions of the eye shows that, as compared with other tissues, unusually high tensions may occur in the aqueous and vitreous. Experimental studies in many animals have revealed a variety of pathologic changes, some of which resemble those found in retrolental fibroplasia. Recent studies have found that these changes are not limited to immature animals.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1964
- Accession Number
- AD0438909
Entities
People
- Cecil C. Beehler
Organizations
- United States Air Force School of Aerospace Medicine