THE SYNTHESIS OF NON-COMMERCIALLY AVAILABLE ORGANIC COMPOUNDS.
Abstract
The purpose of this contract was to synthesize non-commercially available organic chemicals for investigators at the Army Chemical Research and Development Laboratories, Edgewood Arsenal, Maryland. In the main, the assigned compounds were bridged bicyclic aminoketones; with a few exceptions these compounds have been reported previously in the literature. Compounds heretofore unreported but prepared in the course of this contract are 3-oxo-1-azabicyclo (2.2.1) heptane (Compound A-17), 4-oxo-1-azabicyclo (3.2.1) octane (A-18), 2-hydroxymethylpyrrolizidine (A-25) and ethyl 2-hydroxymethylpyrrolidine-1-acetate (A-26). In addition, during the report period a second quantity of 2-keto-octahydropyrrocoline (A-19) was prepared. An effort was made to identify all compounds as fully as possible through IR spectroscopy and refractive index measurements and to ascertain the degree of purity through thin layer chromatography. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 25, 1964
- Accession Number
- AD0439402
Entities
People
- Charles A. Feit
- Eugene R. Carr
- Richard W. Shubart