DETERMINATION OF HYDRAZINE AND 1-METHYLHYDRAZINE IN BLOOD SERUM.

Abstract

A simple procedure is described for measuring microgram amounts of hydrazine in the blood serum of rats. The procedure, with a minor modification, can be used for measuring microgram amounts of 1-methylhydrazine. The report presents calibration ranges of 0.5-5.0 micrograms/ml and 0.5-10.0 micrograms/ml of hydrazine and 1-methylhydrazine, respectively. Data are presented on the dose-blood-level relationship of hydrazine and 1-methylhydrazine in rats following intraperitoneal injection. Minimum detectable dose levels were 0.6 mg/kg and 3.0 mg/kg of hydrazine and 1-methylhydrazine, respectively. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1964
Accession Number
AD0441231

Entities

People

  • Anthony A. Thomas
  • Barbara A. Reynolds

Organizations

  • Air Force Research Laboratory

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Serum
  • Calibration
  • Hazards
  • Hydrazines
  • Materials
  • Propellants
  • Toxic Hazards

Fields of Study

  • Medicine

Readers

  • Aerospace Test and Evaluation
  • Toxicology/Environmental Toxicology