DNA SYNTHETIC RATES AND CHROMOSOME REPLICATION IN GENERATING MARROW CELLS,
Abstract
The normally dividing bone marrow cells of the domestic cat provede suitable material for the examination of DNA replication patterns in individual chromosomes. Autoradiographic studies of chromosomes labeled with tritiated thymidine indicate a direct relation of chromosome size to duration of DNA synthetic activity of the 10 hours of the S period studied. In this same period dividing cells achieved a maximum labeling of 80%. This suggests that a portion of the normally dividing cell population undergoes an arrest of considerable length in the G2 period. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 31, 1964
- Accession Number
- AD0450347
Entities
People
- D. Cranmore
- E. L. Alpen
Organizations
- Naval Radiological Defense Laboratory