FLUORESCENT CELL-COUNTING NEUTRALIZATION TEST FOR PSITTACOSIS

Abstract

A sensitive, precise, and specific serological procedure, the fluorescent cell-counting neutralization test, was developed to detect and to measure quantitatively psittacosis serum neutralizing antibodies within 24 hours. The test is based on the reduction of fluorescent cells in McCoy cell monolayers resulting from the neutralization of infective virus particles by specific antiserum. Small but significant rises in neutralizing titers were measured in serum specimens from monkeys previously exposed to the virus and from humans with diagnoses of subclinical or established infections of psittacosis.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1964
Accession Number
AD0456681

Entities

People

  • Kenneth O. Cooke
  • Nicholas Hahon

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Antibodies
  • Cell Count
  • Cell Line
  • Cells
  • Gram-Negative Bacterial Infections
  • Infection
  • Microorganisms
  • Particles
  • Precision
  • Rodents
  • Serodiagnosis
  • Standards
  • Tissue Culture
  • Virion
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Virology (or Medical Virology).