LOSS IN VIRULENCE OF YELLOW FEVER VIRUS SERIALLY PASSED IN HELA CELL CULTURES

Abstract

Yellow fever virus passed in HeLa cells was characterized for adaptation to growth in cell culture, level of titer, cytopathic effect, stability to aerosolization at 2 humidities, and respiratory infectivity for monkeys. Four viral populations with different combinations of properties were obtained.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1965
Accession Number
AD0458553

Entities

People

  • Henry J. Hearn Jr.
  • William S. Miller
  • William T. Soper

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Airborne
  • Animal Diseases
  • Arbovirus Infections
  • Arboviruses
  • Biological Laboratories
  • Culture Techniques
  • Diseases And Disorders
  • Health Services
  • Infection
  • Lethal Dosage
  • Maryland
  • Munitions
  • Public Health
  • United States
  • Virulence
  • Viruses
  • Yellow Fever

Fields of Study

  • Biology

Readers

  • Virology (or Medical Virology).