Biological Safety Evaluation of a Commercial Vaccine Production Laboratory

Abstract

Operation of buildings and equipment for work with pathogenic microorganisms often involves inherent hazards unknown to personnel responsible for design, construction, budgeting, or research. To a significant extent the facilities and equipment of a laboratory building will aid or deter efforts of operating personnel in maintaining good environmental control and in preventing laboratory infections. The tests reported here were designed to evaluate the microbiological hazards associated with equipment, general building design, construction, operational features, effluent treatment system, and routine research operations in a newly constructed vaccine production facility. The testing procedures and equipment used are described or referenced and the results are tabulated to show the method used to assess the microbiological hazards. The risks to personnel are characterized, and methods are recommended to improve operation of the building as designed, to modify equipment, and to eliminate hazards.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1965
Accession Number
AD0464951

Entities

People

  • Manuel S. Barbeito

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Accidents
  • Air Flow
  • Air Pressure
  • Air Supplies
  • Diseases And Disorders
  • Ducts
  • Efficiency
  • Exhaust Systems
  • Health Services
  • Infectious Diseases
  • Laboratory Equipment
  • Materials
  • Medical Personnel
  • Microorganisms
  • Public Health
  • Test And Evaluation
  • Ventilation Ducts

Readers

  • Aerospace Test and Evaluation
  • Industrial Economics
  • Infectious Disease/Epidemiology

Technology Areas

  • Biotechnology