AGAR-GEL PRECIPITIN-INHIBITION TECHNIQUE FOR PLAGUE ANTIBODY DETERMINATIONS

Abstract

The agar-gel precipitin-inhibition technique of Ray and Kadull can be used to detect plague antibodies in human and animal sera after a series of plague vaccine inoculations or after exposure to Pasteurella pestis. Determination of the minimum reacting concentrations of the plague antigen and antibody reagents, methods for combining reagents, and length of incubation periods are discussed.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1965
Accession Number
AD0465197

Entities

People

  • John G. Ray Jr.
  • Paul J. Kadull

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Bacteria
  • Biological Products
  • Biomedical Research
  • Blood
  • Diffusion
  • Dilution
  • Gammaproteobacteria
  • Immune Serums
  • Inhibition
  • Inoculation
  • Laboratory Animals
  • Reproducibility
  • Sensitivity
  • Therapy
  • Titration
  • Vaccines

Fields of Study

  • Biology

Readers

  • Immunology

Technology Areas

  • Biotechnology