ASCORBIC ACID, BIOLOGICAL FUNCTION AND CHEMISTRY.
Abstract
The objective of this work is to initiate a study on the biochemistry of ascorbic acid. Two major areas have been covered. (a) What are the sequence of events and chemical nature of the oxidation of ascorbic acid (AsH2) to monodehydroascorbic acid (AsH) to dehydroascorbic acid (dAs). (b) What are the metabolically active forms of vitamin C and their role on an enzymic level. Our progress in this work is detailed in three sections of this report: (1) Study of Ascorbate Oxidation. (2) Synthesis of Tritium Labeled Ascorbates. (3) The Ascorbate Enzyme System. In addition, cooperative work on ascorbate assays has been done in connection with the Chemical Division of the Medical Research and Nutrition Laboratories of the Fitzsimons Army Hospital, Denver. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 30, 1965
- Accession Number
- AD0466647
Entities
People
- Bert M. Tolbert
- E. Bell
- N. Levandoski
Organizations
- University of Colorado Boulder