CHANGES IN TOTAL BODY SODIUM, AND BODY WATER DURING ACUTE CHOLERA AND DURING MAINTENANCE THERAPY,
Abstract
Tracer studies of fluid compartment changes were made possible during the 1961 cholera outbreak in Manila, Philippine Islands. TBW, Nae, ECF and intracellular fluid shifts were measured during rehydration therapy and durring controlled periods of diarrheal dehydration. When fecal, urine and estimated insensible losses are replaced by equivalent volumes of isotonic NaCL at a plasma specific gravity of 1.024, some degree of sodium loading occurs. For otherwise normal patients, this would lie within reasonable range of renal compensation. At high fecal outputs, the tracer sodium initially excreted into the gut appears not to be reabsorbed, and it is delayed several hours in appearing in stool. Cholera dehydration causes marked depletion of extracellular water with comparatively small losses from intracellular water. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 29, 1965
- Accession Number
- AD0466772
Entities
People
- A. L. Reyes
- B. E. Vaughan
- C. K. Wallace
- Q. Blackwell
- R. L. Martin
Organizations
- Naval Radiological Defense Laboratory