FETAL LIVER AND THYMUS: ROLES IN THE ONTOGENESIS OF THE MOUSE IMMUNE SYSTEM,

Abstract

Liver cells or thymic grafts from homozygous embryonic mice were subjected to passage through appropriate nonoperated or thymectomized adult F1 hybrids. Passage through a nonthymectomized host was required for maturation of potential immunologically competent cells derived from embryonic liver; this was not true with regard to cells derived from a fetal thymic graft. Cells from embryonic liver were found first in the host thymus while those from thymic grafts appeared to migrate exclusively to peripheral lymphoid tissues. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jun 21, 1965
Accession Number
AD0467682

Entities

People

  • Leonard J. Cole
  • Marvin L. Tyan

Organizations

  • Naval Radiological Defense Laboratory

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Growth (Physiology)
  • Hemic And Immune Systems
  • Immune System
  • Maturation

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Molecular and Cellular Biology