NITROGEN-15 MAGNETIC RESONANCE SPECTROSCOPY. VI. PYRIMIDINE DERIVATIVES,

Abstract

Proton and nitrogen-15 magnetic resonance spectra of several derivatives of pyrimidine have been studied. Long-range (15)N-H couplings were observed in uracil-(15)N2, 2,4-dichloropyrimidine-(15)N2, 2,4-dimethoxypyrimidine-(15)N2, 1-methyl-4-methoxy-2-pyrimidone-(15)N2, and 1-methylcytosine-(15)N3. A particularly large (15)N(1)-C-H coupling (12.5 c.p.s.) has been observed in 2,4-dichloropyrimidine-(15)N2. 1-Methylcytosine-(15)N3 has been shown to exist in the amino tautomeric form and to protonate at N(3) in agreement with previously reported work on 1-methylcytosine labeled only in the amino group. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1965
Accession Number
AD0467861

Entities

People

  • Bryan W. Roberts
  • John D. Roberts
  • Joseph B. Lambert

Organizations

  • California Institute of Technology

Tags

DTIC Thesaurus Topics

  • Agreements
  • Couplings
  • Magnetic Resonance
  • Motion
  • Nitrogen
  • Pyrimidines
  • Resonance
  • Spectra
  • Spectroscopy

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry