PATHOGENESIS OF THE LETHAL EFFECT OF ANTHRAX TOXIN IN THE RAT. 2. MORPHOLOGIC STUDIES

Abstract

Intravenous injections of anthrax toxin consistently produce pulmonary edema, cyanosis, and death in Fischer 344 rats. A light and electron microscopic study of the lungs of rats sacrificed serially after injections of toxin revealed diffuse pulmonary edema with pronounced capillary endothelial cell changes followed by widespread thrombosis of pulmonary capillaries.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1965
Accession Number
AD0468739

Entities

People

  • Francis A. Beall
  • Frederic G. Dalldorf

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Arteries
  • Biological Laboratories
  • Blood
  • Blood Vessels
  • Cells
  • Cellular Structures
  • Endothelial Cells
  • Epithelial Cells
  • Government Procurement
  • Governments
  • Intercellular Junctions
  • Lung Diseases
  • Macrophages
  • Membranes
  • Thorax
  • United States
  • Veins

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Immunology

Technology Areas

  • Microelectronics