LETHAL PROCESSES IN DEHYDRATION OF MICROORGANISMS
Abstract
Approaches to the study of lethal effects of dehydration and relevant experimental results obtained by the author and co-workers since 1958 are summarized informally. The paper includes (1) a working hypothesis of interacting lethal processes from which self-limiting long-term decay curves can be calculated. (2) Preliminary experimental data illustrating the types of information needed for application of the hypothesis. (3) An account of the preparation of simulated aerosols by deposition of cells upon membrane filters. (4) Approaches to the identification of lethal interactions, including the correlation of lethal effects with the colligative properties of simple additives. (5) Illustrative data for Serratia marcescens in the presence of NaC1, LiBr, and urea. (6) Data on short-term decay of washed Serratia marcescens at 13 ambient relative humidities. (7) Preliminary data on the effects of oxygen in accelerating humiditydependent decay and on possible effects of slow residual water transfer.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1965
- Accession Number
- AD0469390
Entities
People
- John B. Bateman
Organizations
- United States Army Biological Warfare Laboratories