CHEMICAL STUDIES IN CONNECTION WITH POTENTIAL SYSTEMIC INSECT-REPELLENTS AND ROPHYLACTIC AGENTS DEPOSITED IN THE SKIN.
Abstract
The subject investigation comprises studies essential for the development of dependable prophylactic agents against pathogenic or physical impairments of the skin, which would reach the epidermal layers in effective concentration after parenteral or peroral administration. It is our endeavor (1) to gain a better understanding of the nature of molecular functions which have a tendency of migrating to and being excreted through cutaneous structures, (2) to study the chemical configuration and characteristics of effective insect-repellents, and (3) to combine, within a single molecule, a component known to have affinity for dermal elements with a component possessing certain insect-repellent properties; in other instances, a molecular component determined to exert skin-toughening (keratinization-enhancing), or sun-light-induced-erythemogenesis-preventing, or certain antibacterial, or certain antifungal properties would take the place of the insect-repellent moiety. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1965
- Accession Number
- AD0470382
Entities
People
- Andrew Lasslo
- Ronald P. Quintana
- Vasu Dev
Organizations
- University of Tennessee