EPIDEMIOLOGICAL AND GENETICAL STUDY ON THE DRUG-RESISTANCE OF SHIGELLAE AND STAPHYLOCOCCI.
Abstract
The strains of Staphylococcus aureus were collected from the in-patients in the 17 hospitals dispersed geographically in Japan. According to the determination of their drug-resistance and phage typing patterns, it was found that the multiple resistance and restricted phage type were predominant in the epidemic strains of St. aureus. There are two types in the degree of drug-resistance, i.e., high- and meso-resistance and the degree of resistance is extremely high in the multiple resistant strains carrying TC resistance. Three types of the resistance to macrolide antibiotics were presented. By the artificial elimination and transductional analysis, it was concluded that the determinants of penicillinase production and of the resistance to macrolide antibiotics are located together on a single genetic element. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- May 14, 1965
- Accession Number
- AD0474990
Entities
People
- Susumu Mitsuhashi
Organizations
- Gunma University