SODIUM TRANSPORT IN ISOLATED ILEUM FROM COBALT-60 IRRADIATED RABBITS

Abstract

The study of sodium transport in isolated ileum from 51 irradiated rabbits reveals no decrease in short-circuit current from 4 to 216 hours after exposure to 1.2 kR and from 4 to 50 hours after exposure to 2.0 kR from a Co60 source. Separate preparations of Adjacent sections of terminal ileum received simultaneous additions of either 10 mM. D-glucose or 10 mM. L-alanine to mucosa and serosa. A normal response in short-circuit current was obtained in the 1.2 kR group, and a large increase in short-circuit current response was observed in the 2.0 kR group after glucose addition. Evidence is presented that the ''sodium pump'' is not blocked after 1.2 kR and 2.0 kR doses of gamma irradiation in isolated rabbit ileum within these time intervals.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1965
Accession Number
AD0477331

Entities

People

  • Arthur E. Gass Jr.
  • John P. Higdon

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Alanine
  • Amino Acids
  • Animals
  • Blood
  • Chlorides
  • Gastrointestinal Tract
  • Governments
  • Intestines
  • Large Intestine
  • New York
  • Radiation
  • Rodents
  • Short Circuits
  • Small Intestine
  • Time Intervals
  • X Rays

Readers

  • Cardiovascular Physiology
  • Electronics Engineering
  • Nuclear and Radiation Engineering.