THE EFFECT OF THYMIDINE POOL SIZE ON THE INCORPORATION OF THYMIDINE INTO DNA AFTER IRRADIATION

Abstract

A model system to explain the effect of irradiation on the incorporation of thymidine into deoxyribonucleic acid (DNA) was studied. The model explains the increase observed in thymidine incorporation after irradiation as due to an increase in the intracellular thymidine pool, coming from DNA breakdown. The data agree with this model.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1965
Accession Number
AD0477333

Entities

People

  • Donald F. Logsdon Jr.
  • Harold L. Kundel

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Acids
  • Aerospace Medicine
  • Air Force
  • Air Force Facilities
  • Automatic
  • Cells
  • Contractors
  • Contracts
  • Deoxyribonucleic Acids
  • Government Procurement
  • Governments
  • Lymphatic System
  • Molecules
  • Nucleic Acids
  • Radiation Effects
  • Standards

Fields of Study

  • Medicine

Readers

  • Molecular Genetics
  • Nuclear and Radiation Engineering.
  • Theoretical Analysis.