RESEARCH AND REPORTS ON EFFECTS OF ALCOHOL AND DRUGS ON RATS UNDER AMBIENT AND LOW TEMPERATURES, MEASURED BY AVOIDANCE RESPONSE.

Abstract

This report summarizes the experimental results obtained in the evaluation of the effects of alcohol and drugs on rats under ambient and low temperatures as measured by avoidance response. Based on LD50 determinations, the toxicity of the tranquilizers, chlorpromazine and chlordiazepoxide, and the sedative hypnotics, morphine and promethazine, increased with acute exposure to cold. The toxicity of amphetamine, a stimulant, was lowered at reduced temperatures. (Author)

Document Details

Document Type
Technical Report
Publication Date
May 31, 1965
Accession Number
AD0477480

Entities

People

  • G. C. Stone
  • K. C. Leung

Tags

DTIC Thesaurus Topics

  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Chlorpromazine
  • Hypnotics And Sedatives
  • Low Temperature
  • Morphine
  • Pharmacologic Actions
  • Test And Evaluation
  • Toxicity

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.
  • Combustion and Flow Dynamics.