STREPTOMYCIN INHIBITION OF ELABORATION OF STAPHYLOCOCCAL ENTEROTOXIC PROTEIN
Abstract
Staphylococcus aureus, strain S-6, under certain cultural conditions, synthesizes and elaborates into the medium an enterotoxic protein. It has been observed that streptomycin interferes with the elaboration of this protein by streptomycin-resistant staphylococci at drug levels permitting continued synthesis of those proteins necessary for growth and multiplication of the organisms. It is likely that the enterotoxic protein is incomplete or that it is not released from the cell because of streptomycin-induced alterations in the cell itself.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1966
- Accession Number
- AD0481024
Entities
People
- Albert J. Rosenwald
- Ralph E. Lincoln