DIFFERENCES IN PROTEIN CONTENTS AMONG FIBROBLAST CELL LINES GROWN IN MONOLAYER CULTURES

Abstract

The changes in cell protein values of cat kidney and McCoy's human synovial cell lines were determined during various phases of monolayer growth in a lactalbumin hydrolyzate - 10% calf serum medium. The McCoy's cell protein values ranged from 1/230 000 000 to 1/574 000 000 mug/cel whereas the cat kidney cell values ranged from 1/131 000 000 to 1/367 000 000 mug/cell. Maximum values for each cell line were recorded during a short period in the lag phase of growth. Essentially constant minimum values were observed after the cultures reached a slowly proliferating, densely populated, post-confluent state. For this reason, the characteristic protein values reported for each cell line were determined during the latter part of the logarithmic growth phase.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1966
Accession Number
AD0481027

Entities

People

  • Kiyoshi Higuchi
  • Raymond R. Galacci

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acids
  • Albumins
  • Amino Acids
  • Anti-Bacterial Agents
  • Biological Pigments
  • Biological Sciences
  • Cell Line
  • Chemistry
  • Culture Techniques
  • Fibroblasts
  • Filtration
  • Indicator Dyes
  • Monomolecular Films
  • Standards
  • Tissue Culture
  • Tissues
  • United States

Fields of Study

  • Biology

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Mathematics or Statistics
  • Virology (or Medical Virology).