Effect of the Container on the Stability of Aqueous Solutions of Pralidoxime Chloride

Abstract

The storage stability of solutions of pralidoxime chloride (2-PAMCl) in metal containers was studied. The metal containers were a component part of the AtroPen Auto-Injector. The oxime was placed in various containers, and its rate of decomposition was observed at ambient temperatures, 40, 65, and 95 deg C. Results are presented graphically. Decreased stability may be used to catalysis by the metallic surface. It the AtroPen Auto-Injector is to be used for the administration of 2-PAMCl solutions, glass or suitable plastic containers should be used.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1965
Accession Number
AD0482946

Entities

People

  • Albert A. Kondritzer
  • Jon R. May

Organizations

  • Edgewood Chemical Biological Center

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Aqueous Solutions
  • Atropine
  • Automatic
  • Catalysis
  • Chemical Reactions
  • Chlorides
  • Containers
  • Decomposition
  • Department Of Defense
  • Health Services
  • Injectors
  • Metals
  • Stainless Steel
  • United States
  • United States Government
  • Water

Readers

  • Materials Science and Engineering.
  • Neurotoxicology
  • Thermal Physics or Thermal Science.