MULTIPLE INFECTION OF CELL MONOLAYERS BY VIRUS MIXTURES

Abstract

The applicability of selective immunofluorescent staining in conjunction with fluorescent cell-counting for the quantitative assay of virus mixtures is described. Multiple infection of cell monolayers was achieved with simultaneous inoculation by yellow fever, variola, and psittacosis agents in mixture. Each agent was assayed independently and no interference of viral growth occurred. Viral interference, manifested by the exclusion of yellow fever virus, was noted when the psittacosis agent and variola virus were inoculated 20 hours before the former.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1966
Accession Number
AD0489043

Entities

People

  • Nicholas Hahon

Tags

DTIC Thesaurus Topics

  • Acids
  • Adsorption
  • Arbovirus Infections
  • Biological Staining And Labeling
  • Chemical Compounds
  • Culture Techniques
  • Gram-Negative Bacterial Infections
  • Immune Serums
  • Infection
  • Inoculation
  • Monomolecular Films
  • Nucleic Acids
  • Proteins
  • United States
  • Viruses
  • Wound Infections
  • Yellow Fever

Fields of Study

  • Biology

Readers

  • Virology (or Medical Virology).