MOLECULAR SIZE OF CLOSTRIDIUM BOTULINUM TOXINS,
Abstract
The molecular size of the various types of Clostridium botulinum toxins in spent culture have been estimated. The estimates were based on the rate of sedimentation of the toxin as measured by mouse assay before and after ultracentrifugation of culture. The results indicate that the molecular size of Type A toxin is the same in culture as that of the purified toxin (MW, 900,000) and that all other types, B through F, also must have molecular weights that approach that of Type A. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1966
- Accession Number
- AD0489045
Entities
People
- Edward J. Schantz
- Leonard Spero