A NEW SYNTHESIS FOR 6-FURFURYLAMINO-9-BETA-D-RIBOFURANOSYL PURINE (KINETIN RIBOSIDE)

Abstract

Kinetin riboside is of interest in plant physiology as a mitotic stimulant and in the tissue culture of cancer cells for its unusual differential toxicity toward adult human fibroblasts in the presence of human carcinoma cells. Three multi-step methods for its synthesis have been reported. This report describes a simple two-step synthesis for kinetin riboside that, unlike the cited methods of preparation, utilizes intermediates that are readily available and requires only a fraction as much time and effort for completion. Authentic kinetin riboside and material prepared by this synthesis were subjected to a number of physical and chemical tests and the data thus obtained are compared.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1966
Accession Number
AD0489059

Entities

People

  • George Svarnas
  • Herman Rutner

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Aluminum
  • Aluminum Hydride
  • Biological Sciences
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Diesel Fuels
  • Hydrides
  • Hydrochloric Acid
  • Hydroxides
  • Materials
  • Melting Point
  • New York
  • Nucleosides
  • Organic Chemistry
  • Physiology
  • Three Dimensional

Fields of Study

  • Chemistry

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  • Molecular and Cellular Biochemistry