THE RESPONSE OF THE THYROID GLAND TO A LOW ENVIRONMENTAL TEMPERATURE AS STUDIED WITH RADIOIODINE
Abstract
Limited studies by this laboratory of basal metabolic rates of men exposed to cold in an Arctic environment did not reveal any demonstrable change in energy metabolism. In order to determine the effects of varying amounts of cold exposure on thyroid function, studies were carried out on rats using the uptake of radioiodine as a measure of the functional activity of the gland. Male rats were exposed to 4 + or - 0.5 C for periods of from 2 hours through 60 days. A diminished amount of radioiodine was found to be present in the experimental animals at exposure intervals under 6 hours. The amount present at about 6 hours was the same as for the controls and increased after 12 to 24 hours. The increased uptake was most pronounced at 7 to 9 days and gradually returned to control values by 40 days.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1949
- Accession Number
- AD0493349
Entities
People
- A. T. Krebs
- H. G. Schachner
- Z. S. Gierlach
Organizations
- United States Army Medical Research Laboratory