An Investigation into the Use of Immobilised Cholinesterase for the Automatic Detection of Nerve Agents
Abstract
The automatic detection of nerve agent vapors using cholinesterase covalently bonded to a modified polymethacrylate ion exchange resin and incorporated into an absorbent permeable paper, is described. The system responds to G-agent concentrations as low as 0.005 mg/cum in under 5 minutes and to high agent concentrations in 5 - 8 seconds. The electrochemical method used to monitor the inhibition of enzymic activity has been studied and the problems associated with electrode design and the ability to achieve a stable operating baseline are discussed. A rapid photometric method for the assay of insoluble cholinesterase is described.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1971
- Accession Number
- AD0595689
Entities
People
- C. Stratford
- E. J. Olsen
- G. Williams
- James H. Lambert