THE LONG TERM EFFECTS OF NEUTRON EXPOSURE ON BONE GROWTH IN THE RAT.
Abstract
The long term effect of fast neutron exposure on bone growth in terms of femur, tibia and tail length was studied in male rats using a roentgenographic measurement technique. There was a growth deficit evident in all three structures of irradiated animals at the end of life span. The magnitude of the reduction in bone length was dependent upon the radiation dose and the age of the animal at the time of exposure. For animals exposed at the same age, the magnitude of the bone length deficit varied directly with dose. For animals exposed to the same dose, the effect was greater in juvenile animals than it was in young adult animals. The greater stunting effect of neutron exposure on bone growth in animals exposed as juveniles compared to animals exposed as young adults was explained on the basis of the faster growth rate of the juvenile animals at the time of exposure. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 25, 1964
- Accession Number
- AD0600171
Entities
People
- D. J. Kimeldorf
- R. D. Phillips
Organizations
- Naval Radiological Defense Laboratory