RESEARCH ON DRUGS ON NEURONAL TRANSMISSION.
Abstract
The actions of centrally active drugs and related compounds on transmission across the synapses of the superior cervical ganglion of the cat, rabbit and rat have been studied because these synaptic junctions may be regarded as being closely allied to those seen between central neurones. Experiments on the cat ganglion were made in vivo with repetitive preganglionic nerve stimulation while those on the isolated ganglia of the rabbit and the rat were made in vitro and usually involved the application of single stimuli to the preganglionic trunk with recording of the evoked ganglionic or postganglionic action potentials. The results are summarized in 2 parts firstly, quantitative findings and secondly, qualitative observations with particular reference to modes of action. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1964
- Accession Number
- AD0600227
Entities
People
- J. P. Quilliam
Organizations
- University of London