INVESTIGATION OF THE MECHANISM OF ACTION OF RYANODINE ON MAMMALIAN SKELETAL MUSCLE.

Abstract

Efforts to isolate, from granule suspensions incubated with MG(++) and ATP, a chemical substance capable of relaxing contracted muscle fibers were unsuccessful. Conditions were established under which ryanodine increased by a factor of two or more the time required for fiber bundles to relax after addition of calcium to the bath containing ATP, MG(++) and granules.

Document Details

Document Type
Technical Report
Publication Date
May 08, 1964
Accession Number
AD0600282

Entities

People

  • John I. White

Organizations

  • University of Maryland, Baltimore

Tags

DTIC Thesaurus Topics

  • Alkaloids
  • Anatomy
  • Biological Sciences
  • Muscle Fibers
  • Muscles
  • Musculoskeletal System
  • Skeletal Muscle
  • Tissues

Fields of Study

  • Biology

Readers

  • Materials Science and Engineering.
  • Microbial Pathology
  • Thin Film Deposition Science.