OBSERVATIONS ON ACUTE AND CHRONIC OXYGEN POISONING.

Abstract

In an effort to discover the relationship between the occurrence of convulsions (acute effects) caused by oxygen at high pressure (OHP), and paralysis (chronic effects), susceptible rats have been repeatedly exposed to OHP under conditions that would tend to lessen the tendency toward the occurrence of convulsions. One group was lightly anaesthetized (10 mg/kg Nembutal) and the other exposed for a short time to maximum pressure and slowly decompressed. Of the anaesthetized animals, two developed paralysis without having exhibited any previous acute (convulsive) effects while four developed paralysis with only slight acute effects. All of the slowly decompressed rats convulsed and only two showed paralysis. These observations indicate that paralysis and convulsions are not necessarily associated symptoms of oxygen toxicity. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 21, 1964
Accession Number
AD0600773

Entities

People

  • George H. Kydd
  • L. H. Betz

Organizations

  • Naval Air Warfare Center Warminster

Tags

DTIC Thesaurus Topics

  • Diseases And Disorders
  • High Pressure
  • Memory Devices
  • Nervous System Diseases
  • Neurologic Manifestations
  • Observation
  • Paralysis
  • Poisoning
  • Seizures
  • Signs And Symptoms
  • Symptoms And General Pathology
  • Toxicity

Readers

  • Toxicology/Environmental Toxicology
  • Underwater engineering and Marine Technology.