CHRONIC EFFECTS OF IONIZING RADIATION ON THE HEMATOPOIETIC SYSTEM.

Abstract

The cellular and biochemical basis for the cumulative damage manifested in the immature and mature female rats during their maintenance in the selected low level gamma radiation environments were studied. Frequent quantitative measurements were made of the cellular composition of blood and blood forming tissues and of the major protein components of serum. Massive recovery of splenic erythropoiesis under continuous radiation exposure in the absence of marrow recovery was noted. This pointed to a potential role of the spleen for survival under the experimental conditions used, and comparisons of splenectomized with non-splenectomized animals were also performed. Experiments have been started to provide information on post-radiation survival after continuous exposure to ascertain late effects of radiation including stress situations such as heat and cold. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1964
Accession Number
AD0602135

Entities

People

  • Charles E. Brambel

Organizations

  • University of Notre Dame

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Blood
  • Body Fluids
  • Environment
  • Erythropoiesis
  • Fluids And Secretions
  • Gamma Rays
  • Hematopoietic System
  • Hemic And Immune Systems
  • Ionizing Radiation
  • Lymphatic System
  • Maintenance
  • Radiation
  • Recovery
  • Survival

Readers

  • Cardiovascular Physiology
  • Immunology and Pathology
  • Nuclear and Radiation Engineering.