PHYSIOLOGICAL AND ENVIRONMENTAL INFLUENCES ON THE METABOLISM OF THYROID HORMONES.
Abstract
The nature of adaptations in thyroid function and in particular the peripheral metabolism of thyroid hormones which participate in physiological and environmental alterations in bodily economy (heat and cold exposure, exercise, prolonged emotional stress, prolonged fasting, etc.), are studied. The interplay of the metabolic actions of thyroid hormones on adaptive, homeostatic mechanisms (renal concentrating mechanisms, metabolism of vasopressin, effects on substrate balance in fasting, etc.), is also considered. Specific topics include: (1) the comparative physiology of thyroid hormone metabolism, (2) studies of the acute phase distribution and metabolism of thyroxine in man, (3) the effects of thyroid hormone on the renal concentrating mechanism, (4) studies of substrate balance in fasting man, and studies of anterior pituitary metabolism in vitro.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 30, 1964
- Accession Number
- AD0602992
Entities
People
- C. J. Goodner
- J. Thomas Dowling
- R. E. Cutler
Organizations
- University of Washington