AN NMR STUDY OF THE PROTOLYSIS KINETICS OF GLYCINE.
Abstract
The exchange of protons between the amino group of glycine and aqueous solvent was investigated by means of its effect upon the proton high resolution n.m.r. spectrum of the methylene group. The mean lifetime between exchanges of protons in the NH3(+) group was measured at room temperature as a function of glycine concentration and of hydrogen ion concentration. Similar studies were made of the glycine methly ester. Several mechanisms contributing to the exchange proved to be separable by means of the changes in mean lifetime with pH and glycine or ester concentration, and rate constants were obtained for the reactions. A brief comparison of these results with those obtained for other amino acids and for simple amines indicates that the proton exchange mechanism for positively charged amino groups in strongly acidic solutions are the same for the several types of such systems studied so far. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- May 28, 1964
- Accession Number
- AD0603586
Entities
People
- Herbert S. Gutowsky
- M. Sheinblatt
Organizations
- University of Illinois Urbana–Champaign