ENDOCRINE AND METABOLIC RESPONSE OF DOGS TO WHOLE-BODY VIBRATION.

Abstract

To determine the endocrine and metabolic response of restrained dogs to whole-body vibration, pentobarbital anesthetized and non-anesthetized dogs were vibrated along the z axis while restrained in dorsal recumbency. After vibration of anesthetized dogs at either 4 cps, 0.4 g for 30 minutes or 2 hours, or at 10 cps, 2.3 g for 2 hours, there was an average increase of 4.08 mcg 17 hydroxycorticosteroids (17-OH-CS) per 100 ml plasma and a significant increase in blood epinephrine but not serotonin or norepinephrine. Shaking at 4 cps, 1.7 g for 30 minutes produced less of a change in plasma 17-OHCS than at 0.4 g. However, shaking at 4 cps for 6 hours led to greater increase in plasma 17-OH-CS at 1.7 g than 0.4 g. Non-anesthetized dogs shaken at 4 cps for 30 minutes had a greater increase of plasma 17-OH-CS than similarly shaken anesthetized dogs. Possible mechanisms for alterations in endocrine function are discussed. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1964
Accession Number
AD0606054

Entities

People

  • Ben B. Blivaiss
  • Giorgio Galansino
  • Piero P. Foa
  • Renato Litta-modignani

Organizations

  • University of Chicago

Tags

DTIC Thesaurus Topics

  • Amines
  • Aromatic Compounds
  • Catecholamines
  • Chemical Compounds
  • Chemistry
  • Epinephrine
  • Norepinephrine
  • Organic Compounds
  • Phenols
  • Serotonin
  • Vibration

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Structural Dynamics.
  • Toxicology/Environmental Toxicology